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KMID : 0368820150540020252
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Journal of the Korean Neuropsychiatr Association
2015 Volume.54 No. 2 p.252 ~ p.256
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A Case of Clozapine-Induced Anemia and Thrombocytosis
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Jeon So-Yeon
Park Han-Son
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Abstract
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Clozapine is a well-known antipsychotic which causes hematologic adverse effects, specifically neutropenia and agranulocytosis (1-3% of patients). However, reports on blood dyscrasias like anemia and thrombocytosis after clozapine treatment are extremely rare. In some cases re-challenge of clozapine could lead to hematopoietic abnormality related to thrombocytopenia or thrombocytosis, which may be a result of an immune reaction. This case report suggests that clinicians should monitor platelet count after re-treatment with clozapine.
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KEYWORD
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Clozapine, Anemia, Thrombocytosis, Blood dyscrasia
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